COVID Town Hall II

(If no image, or larger screen is desired, watch on YouTube at https://youtu.be/O2Aa5vEYywU)

This is a video of a COVID Town Hall Zoom meeting hosted by Dr. Mike Nichols on May 20, 2020. The following topics are covered:

Overview: The coronavirus is not some weird new thing. It is a normal virus, though dangerous. Dangerous, but not as bad as ebola.

Understanding risk:

  • Statistics don’t make sense because we are dealing with multiple strains.
  • R0 depends on demographics
  • Lethality. Thought to be 0.5%. Not enough data to know for sure. 0.4 to 0.7 per 100,000 daily death-rate. Total all cause morbidity is 900/100,000 per year.
  • Acute phase reactance. Inflammation numbers show this. Liver produces cascade of inflammatory/anti-inflammatory. Can trigger strokes, etc. Not unique to COVID

Spread of disease.

  • Super-spreaders. Someone with a lot of contact. A bartender, for instance. Testing and tracking makes sense here. IMO tracking does not make sense for the US generally.
  • Droplets –
  • Fomites – stuff on the floor, the doorknob
  • Use these to arrive a risk strategy

We do not know the infectious dose. Probably not as bad as originally though.

Therapies and immunizations.

Immunizations

  • Not optimistic because of common cold and flu. The virus changes.
  • Maybe partial immunity.
  • We will learn a lot about viral science.
  • There might be a weak spot. Not known.

Therapies

  • Remdesivir is not that great.
  • At this point, any therapy will have to be cocktail
  • Zinc is helpful. Can be bad if used daily. Use only when infected.
  • Vitamin D confers meaningful protection.

Risk factors.

  • Not enough info.

Exercise and COVID

  • Exercise lessens risk of obesity
  • Challenge mitochondria to make them stronger. Interval training does this.
  • Sustained sub-maximal work also does this.
  • Types of exercise: Tempus protocols.

Mental state

  • Has big impact on immune system
  • Training will improve mood
  • Spiritual discipline (SD). This means quieting the mind. Inner silence.
  • Measure

Sleep

  • Can’t live without air, sleep, water, and food.
  • No sleep can kill.
  • Make sure to get enough sleep. Water, food

Food.

  • Choose and anti-inflammatory diet. Insulin raisers are inflammatory=sugar&starch.

Questions and Answers

Note: Some charts will be displayed. The default resolution may not be adequate to view these charts, but by clicking the settings gear, a higher resolution may be selected.

About masks. Bandana with coffee filter? None are perfect. Any mask helps. The more effective the better. Any mask will protect others.

Incremental immunity. Not known now. The virus will be around at least two years.

How often to test. Depends on whom one might expose. If you think there is some risk you have been exposed, get a test. Testing should be more widely available. Hugging carries a risk as stuff may be on clothes.

Exercising without a rowing machine. Hill run, jump rope, step-ups, stairs.

Prognosis. Referring to Johns Hopkins COVID dashboard. Amount of testing won’t indicate background level of infection. Projections of 150,000 deaths by August may be low. There is East coast/West coast strain. Difference is China versus European strain. Different strains in different parts of the country. Lethality is 5x flu, more likely 10x. So several hundred thousand deaths per year.

Overtraining will increase risk. Undermines immune system.

 

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