Are SGLT2 Inhibitors a Bad Idea?

SGLT2 Inhibitors are the Latest Treatment for Adult Onset Diabetes. However, Many Treatment, Like Insulin, Have Done More Harm Than Good. Caution is Advised.

Brilliant basic science research continues its quest to understand human physiology. Pharmaceutical science continues its quest to cash in on the latest basic science discoveries. I want to illustrate this specifically with SGLT2Nephron inhibitors. In that setting I also want to ask what is the ethical duty of the medical profession towards those suffering with Adult Onset Diabetes Mellitus (AODM)?

SGLT2 inhibitors block the type 2 sodium-glucose-transport system in the kidneys. What the heck is that?

Adult Onset Diabetes Basics

VIRTUALLY ALL ADULT ONSET DIABETES CAN BE CURED BY LIFESTYLE CHANGE

Adult Onset Diabetes (AODM), sometimes called Type II Diabetes, refers to a situation where the body cannot secrete enough insulin to keep sugar at a healthy level. How does that work?fgdg

Circulating Glucose (Sugar) Is Tightly Regulated

Circulating blood glucose (sugar) is tightly regulated by a tiny brain called the hypothalamus. All vertebrates, including us, have these tiny brains. It’s the size of an almond and right in the center of your skull. By regulated, we mean that the hypothalamus will make adjustments to attempt to keep glucose at an ideal level of 80 mg/dl.

Cholesterol Basics – Myths and Medical Facts

CHOLESTEROL: MYTHS, ITS PURPOSE, WHAT’S IMPORTANT, WHAT’S NOT

Cholesterol has received more negative attention in the last 30 years than it ever deserved. Let’s start by dispensing with two major medical myths:

dfgsdgMYTH 1: Eating foods high in cholesterol will raise your cholesterol. THIS IS NOT TRUE. You can have all you want. It won’t affect your cholesterol level.

MYTH 2: High cholesterol causes heart disease. THIS IS NOT TRUE. Heart disease is caused by abnormally small lipoprotein particles. These are called LDL, and are a mix of fat, cholesterol, and some proteins. It is not the content that is important, it is the size. The small sizes are problematic, and it is primarily the fat in the particles that does the damage. The size, in turn, is controlled by diet.

Nuts, Baby Aspirin, and Statins – Which is Best?

NUTS, BABY ASPIRIN, AND STATINS

All three of these reduce cardiac events by around 35%. However the groups benefited and the side effects are vastly different.

NutsAspirinStatins

 The nut industry is now prominently displaying a “Heart-Healthy” symbol on their products, and for good reason: Of the three ‘medicines’ mentioned above, nuts are the most effective at reducing heart attacks and have the least side effects. In fact, unless you are allergic to them, they have no side effects at all.

Saturated Fat – It’s Healthy – It’s Not Dangerous

SATURATED FAT IS GOOD FOR YOU

Yes, you read that right. Saturated fat is GOOD for you. Now before you dismiss this as pure quackery, here are a couple of qualifications:sat

  • Trans-fat, often associated with saturated fat, is bad for you, quite bad for you in fact.
  • Saturated fat from animals raised in unsanitary conditions (feed lots, for instance), may be loaded with all sorts of undesirable stuff.
  • Saturated fat is a political hot potato for reasons having little to do with health or nutrition.

Who Gets Degenerative Disease?

WHO GETS DEGENERATIVE DISEASE AND WHO IS SPARED?

In the west – Europe and North America – more than 70% die from degenerative disease, yet there are two identifiable groups that are largely free from thesedege.deg

By degenerative disease we mean heart disease, cancer, adult onset diabetes, dementia, and several less common age related diseases.

We know for certain that degenerative disease can be avoided. These groups, and their lifestyles are proof. The two groups are hunter-gatherers and centenarians.