Off Label Drug Use

The Use Of Prescription Medications To Treat Problems Beyond What The Drugs Were Originally Approved For Is Widespread, With off-label-ballsSome Blessings And Many Dangers.

That an MD will prescribe a drug for use other than that for which it was originally approved comes as a shock to many. In fact, the practice is so widespread that few physicians give it a second thought. The drug companies are all in favor of this, needless to say. Sometime the consequences are beneficial, and sometimes disastrous.

Do Statins Cause Diabetes?

A New Study Has Statin Use Increasing Adult Onset Diabetes by 46%. Earlier statins-cause-AODM-just-say-nostudies had a 10% to 20% increase. Why the difference? And why are statins still prescribed

Numerous studies have shown no benefit from statin use. The most recent one, reported in MedScape, shows a rather horrifying increase in adult onset diabetes: “Statin therapy appears to increase the risk for type 2 diabetes by 46%, even after adjustment for confounding factors.” The study looked at a six-year time frame and followed almost 9,000 people that had started statins. The study seems quite well done. The result is markedly higher than previously reported incidence of diabetes among statin users.

Rosuvastatin (Crestor) Has Little Overall Benefit And Has Many Problems

Rosuvastatin lowers cholesterol more than all the other statins, and because of this, it was hailed as a breakthrough drug. With a huge advertising budget behind it, it became a blockbuster—the top selling statin. But it has a checkered past, and as time goes by, more and more problems seem to be turning up, and less and less benefit is evident.crestor-pills-money

Rosuvastatin’s presumed benefit was its extreme lowering of LDL cholesterol, like from 120 to 55. A lot. A decade ago, it was widely believed that cholesterol was some sort of toxin, and so the less of it the better. This thinking has been substantially revised, for reasons we will get to in a moment.

Beta Blockers: The Problem Drug Is Dangerous

Beta Blockers Help No One, Harm Many, and Should Be Banned

In one previous post, I was screaming, and in another, I was tearing my hair out. In this one I am doing both.

There is a handy web site called NNT means Number Needed to Treat. For example, if 200 need to take a drug so that 1 might avoid a heart attack, the NNT is 200.  If the Beta Blocker
drug that prevents heart attacks does not harm, then ‘why not?’ Statins have an NNT of about 300. However, they do harm to about 1 in 10, but (at least in the eyes of the pharmaceutical industry) that harm is less than the benefit. In any case, the NNH, or Number Needed to Harm, for statins is 10. (But I am not writing this post to rail once more about statins, but do promise endless future posts on this till statins go away.)

Insulin Therapy for Adult Onset Diabetics

Insulin Therapy Should Be Illegal

Some things make me want to scream. In Adult Onset (Type II) Diabetes, glucose regulation has hit the limit. Normally, if the body consumes glucose (sugar or starchy food), the blood Insulin therapyglucose level will rise. In response to this, the body will secrete insulin in an attempt to regulate and bring glucose levels down to around 80 mg/dl. This is about a teaspoon of sugar in the 5 quarts of blood most people have. This is a pretty critical level and important for overall health.

Are New Drugs a Hopeless Search for the Fountain of Youth?


The Search for the Fountain of Youth continues, only, instead of an elixir, it will take the form of a pill, (better shelf-life, lower shipping costs, better profits, etc.) People expect pills will be found to make them well. This is ingrained, and is indeed the case for antibiotics.miracleCure

However, a lot of modern disease does not involve a bacterial or viral infection. Most, perhaps as much as 90%, is the result of a biological system that is overloaded to such an extent that its natural response is as if there were an invading pathogen. Here I am talking about cancer, heart disease, and adult onset diabetes. All of these diseases are either caused directly, or strongly promoted by, a lifestyle that floods cells with excess sugar, excess insulin, excess fat, excess cortisol, and many other hormones.