DRUGS AND SUPPLEMENTS

Off Label Drug Use

The Use Of Prescription Medications To Treat Problems Beyond What The Drugs Were Originally Approved For Is Widespread, With off-label-ballsSome Blessings And Many Dangers.

That an MD will prescribe a drug for use other than that for which it was originally approved comes as a shock to many. In fact, the practice is so widespread that few physicians give it a second thought. The drug companies are all in favor of this, needless to say. Sometime the consequences are beneficial, and sometimes disastrous.

Do Statins Cause Diabetes?

A New Study Has Statin Use Increasing Adult Onset Diabetes by 46%. Earlier statins-cause-AODM-just-say-nostudies had a 10% to 20% increase. Why the difference? And why are statins still prescribed

Numerous studies have shown no benefit from statin use. The most recent one, reported in MedScape, shows a rather horrifying increase in adult onset diabetes: “Statin therapy appears to increase the risk for type 2 diabetes by 46%, even after adjustment for confounding factors.” The study looked at a six-year time frame and followed almost 9,000 people that had started statins. The study seems quite well done. The result is markedly higher than previously reported incidence of diabetes among statin users.

Rosuvastatin (Crestor) Has Little Overall Benefit And Has Many Problems

Rosuvastatin lowers cholesterol more than all the other statins, and because of this, it was hailed as a breakthrough drug. With a huge advertising budget behind it, it became a blockbuster—the top selling statin. But it has a checkered past, and as time goes by, more and more problems seem to be turning up, and less and less benefit is evident.crestor-pills-money

Rosuvastatin’s presumed benefit was its extreme lowering of LDL cholesterol, like from 120 to 55. A lot. A decade ago, it was widely believed that cholesterol was some sort of toxin, and so the less of it the better. This thinking has been substantially revised, for reasons we will get to in a moment.

Acetaminophen – Should this Dangerous Drug be Available Over the Counter?

Acetaminophen, the principle drug in several popular painkillers, has caused liver damage in many, and liver failures and death in a few. This is a pretty grisly track record for an over-the-counter remedy. Mixing it with alcohol is especially dangerous.tylenol-warning

I stayed at a bed and breakfast in Iceland, and as I was being shown around, I noticed a large bottle of Excedrin labeled “Hangover Pills”. When I mentioned to the owner that acetaminophen in combination with excess alcohol, was responsible for several hundred deaths annually in the US alone, she turned white as a sheet. She had no idea that such a commonly used drug could pose such dangers. She immediately removed the bottle.

Antioxidants – Seldom Useful, Often Harmful

ANTIOXIDANTS AND ARROGANCE

Medical science always thinks it knows better that hundreds of million years of evolution. In the human body – heck any living creature’s body – everything has a purpose, has a reason for being tfhadfh

The identification of various ‘demons’ by the high priests of medicine probably goes back to our ancient caveman days. But how is the demon identified? In the past, it could be by decree, the most important shaman deciding what is and what is not important.

Beta Blockers: The Problem Drug Is Dangerous

Beta Blockers Help No One, Harm Many, and Should Be Banned

In one previous post, I was screaming, and in another, I was tearing my hair out. In this one I am doing both.

There is a handy web site called www.theNNT.com. NNT means Number Needed to Treat. For example, if 200 need to take a drug so that 1 might avoid a heart attack, the NNT is 200.  If the Beta Blocker
drug that prevents heart attacks does not harm, then ‘why not?’ Statins have an NNT of about 300. However, they do harm to about 1 in 10, but (at least in the eyes of the pharmaceutical industry) that harm is less than the benefit. In any case, the NNH, or Number Needed to Harm, for statins is 10. (But I am not writing this post to rail once more about statins, but do promise endless future posts on this till statins go away.)