DISEASE

Are SGLT2 Inhibitors a Bad Idea?

SGLT2 Inhibitors are the Latest Treatment for Adult Onset Diabetes. However, Many Treatment, Like Insulin, Have Done More Harm Than Good. Caution is Advised.

Brilliant basic science research continues its quest to understand human physiology. Pharmaceutical science continues its quest to cash in on the latest basic science discoveries. I want to illustrate this specifically with SGLT2Nephron inhibitors. In that setting I also want to ask what is the ethical duty of the medical profession towards those suffering with Adult Onset Diabetes Mellitus (AODM)?

SGLT2 inhibitors block the type 2 sodium-glucose-transport system in the kidneys. What the heck is that?

Adult Onset Diabetes Basics

VIRTUALLY ALL ADULT ONSET DIABETES CAN BE CURED BY LIFESTYLE CHANGE

Adult Onset Diabetes (AODM), sometimes called Type II Diabetes, refers to a situation where the body cannot secrete enough insulin to keep sugar at a healthy level. How does that work?fgdg

Circulating Glucose (Sugar) Is Tightly Regulated

Circulating blood glucose (sugar) is tightly regulated by a tiny brain called the hypothalamus. All vertebrates, including us, have these tiny brains. It’s the size of an almond and right in the center of your skull. By regulated, we mean that the hypothalamus will make adjustments to attempt to keep glucose at an ideal level of 80 mg/dl.

Nuts, Baby Aspirin, and Statins – Which is Best?

NUTS, BABY ASPIRIN, AND STATINS

All three of these reduce cardiac events by around 35%. However the groups benefited and the side effects are vastly different.

NutsAspirinStatins

 The nut industry is now prominently displaying a “Heart-Healthy” symbol on their products, and for good reason: Of the three ‘medicines’ mentioned above, nuts are the most effective at reducing heart attacks and have the least side effects. In fact, unless you are allergic to them, they have no side effects at all.

Who Gets Degenerative Disease?

WHO GETS DEGENERATIVE DISEASE AND WHO IS SPARED?

In the west – Europe and North America – more than 70% die from degenerative disease, yet there are two identifiable groups that are largely free from thesedege.deg

By degenerative disease we mean heart disease, cancer, adult onset diabetes, dementia, and several less common age related diseases.

We know for certain that degenerative disease can be avoided. These groups, and their lifestyles are proof. The two groups are hunter-gatherers and centenarians.

Which Chronic Diseases Can be Cured

WHAT CAN BE FIXED WITH QUANTITATIVE MEDICINE?

You are no doubt thinking: Lifestyle changes may be unpleasant. I like my life now, but I do want peak health.  If I make all of the changes you suggest and fix my numbers, is that really going touhgdc modify my health. Will it really increase my longevity and prevent degenerative disease?

The somewhat hand-waving answer is: statistically – it definitely will. Results will vary depending on four things: