MODERN MEDICINE

Rosuvastatin (Crestor) Has Little Overall Benefit And Has Many Problems

Rosuvastatin lowers cholesterol more than all the other statins, and because of this, it was hailed as a breakthrough drug. With a huge advertising budget behind it, it became a blockbuster—the top selling statin. But it has a checkered past, and as time goes by, more and more problems seem to be turning up, and less and less benefit is evident.crestor-pills-money

Rosuvastatin’s presumed benefit was its extreme lowering of LDL cholesterol, like from 120 to 55. A lot. A decade ago, it was widely believed that cholesterol was some sort of toxin, and so the less of it the better. This thinking has been substantially revised, for reasons we will get to in a moment.

Number Needed to Treat – Does Your Drug Work?

Number Needed to Treat, or NNT is the number of people that have to take a drug in order for a single person to have a benefit.NNT

The concept of Number Needed to Treat or NNT may surprise you. If 500 people have to take a drug in order that 1 is spared a heart attack, isn’t that the same as saying: The drug is useless for 499 of 500 people that take it. Useless. Well, that’s only if the drug does no harm, but few drugs are this benevolent.

Evolocumab – do we really want to reduce cholesterol?

Again the drug industry has got a new cholesterol reducing drug, and again, heart ‘events’ are reduced, and most likely, something else is increased – but what? Well, once again, we’ll probably have to wait 20 years to find out.Evolocumab-leeches

When leeches failed to cure dropsy, we suppose some medieval physicians recommended, with full solemnity and confidence, more leeches. Or would this be the solution proffered by the leech-mongers?

Useful Medical Gadgets – Measure and Monitor Yourself

At Quantitative Medicine, we love measurement. Want to be a QM do-it-yourselfer? Here is a selection of gadgetry, some useful, and some otherwise that I have tried out. Please let us know of any gadget we omitted and we will duly evaluate them and post a sequel.

Heart Rate Monitor.HR Mon

This one is important for exercise. Specifically, it is important to know maximum heart rate, resting heart rate, and how much the heart rate goes down 1 minute after peak exercise. The ‘leader’ in heart rate monitors is Polar. The monitors are a bit pricey and not awfully user friendly.

Is American Health Care Really That Bad?

The Untied Nations WHO has America Ranked as #37. American doctors tend to reject this number. Here is an analysis and results from several other lists.

A recent post about a U.S. medical policy maker who will decline health care after 75 also noted that the World Health Organization ranked U.S. health care #37. This led to the following reactions:

Noted L.A. oncologist, “…on the other hand, I refuse to subscribe to the tenant that American healthcare is #37 in the world.  That is a ridiculous and otherworldly conclusion.  You [Dr. Mike] and I both know that can’t be true.”